MGY377H1 Midterm: Study notes for midterm
24 Dec 2011
School
Department
Course
Professor
Document Summary
Cells grow in one direction, elongating does not get wider. Can be grown normally at one temp and then switched to non-permissive temperature to study how loss of factor affects the cell. Rod-shaped bacteria grow side-walls and septa in two separate steps. As cell grows longer, new peptidoglycan is incorporated along the walls of the cell. Septum formation at the appropriate time the rod-shaped cell switches to synthesized the division septum. Components: pbp2 transpeptidase/transglycosylase, murg enzyme in synthesis of the lipid-ii peptidoglycan precursor, roda/mray make channel, mreb bacterial actin homolog proposed to make filaments inside cell. Inhibition of elongase complex leads to round shaped cells: can occur through mutations of any proteins of this complex. Components: pbp3 transpeptidase and transglycosylase, murg enzyme in synthesis of lipid-ii peptidoglycan precursor, mray makes channel, ftsz bacterial homolog of eukaryotic tubulin proposed to make filaments inside cell that form a ring.
