MGY377H1 Study Guide - Final Guide: Antonie Van Leeuwenhoek, Viral Envelope, Agostino Bassi

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Unit 1 scope of the problem smallpox. The germ theory of disease: edward jenner (1749-1823) Developed use of cowpox to vaccinate against. First truly effective intervention against a microbial disease: ignax semmelweis (1818-1865) Childbed fever typically killed 10% of women who gave birth in hospitals at that time. Two clinics in the hospital had starkly different mortality rates: the one with doctors killed more patients than the clinic run by midwives. Realized that many doctors were performing autopsies on dead patients and then attending deliveries of babies without washing sometimes with blood still on their hands: agostino bassi (1773-1856) Weevil at various stage of infections with muscardine a group of fungal pathogens that kill different species of insects: robert koch (1843-1910) German physician and founder of modern bacteriology . Developed modern methods for working with microbes in labs. The microbe must be found in all organisms suffering from the disease, but should not be found in healthy organisms.