NFS284H1 Study Guide - Final Guide: Basal Metabolic Rate, Lean Body Mass, Energy Economics

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Cancer: disease characterized by a series of genetic mutations that result in a cell that: Insulin: stimulates the growth of cells, suppresses apoptosis. Estrogen: stimulates the growth of breast tissues, in post-menopausal women, stimulates the growth of breast tumors, circulation in the blood: Bound to sex hormone binding globulin (shbg) Less bioavailable less stimulation of cell growth. Free estrogen not bound to shbg. More bioavailable more stimulation of cell growth. Excessive production of cholesterol in the liver. Deposition of solid cholesterol in gall bladder. Also a consequence of rapid weight loss: rapid loss of body fat increases cholesterol synthesis. Interruptions of breathing during sleep results in poor sleep and excessive fatigue during the day. Fatty tissue in neck compresses the airway and blocks airflow. Osteoarthritis: breakdown of cartilage that cushions the joints, weight increases risk because of excessive pressure on joints. Gout: uric acid deposition in joints, increased risk with insulin resistance, obesity.

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