NFS382H1 Study Guide - Quiz Guide: Phosphate, Calcitriol

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1. Low calcium and high phosphate levels in patients with end stage kidney disease
have increased bone turnover, hence producing more fragile bones. When on
dialysis, the excess phosphorus would be NOT filtered out of the body and excreted
via urine, thus these patients must monitor their dietary phosphorus intakes. This
affects the action of PTH hormone, but the extent depends on the stage of kidney
disease.
2. 300mg.
a. Additives are commonly added to many foods, so there was definitely some
inorganic phosphate included.
3. Low phosphorus diets are only beneficial to people with irregular kidney function, as
they cannot excrete the excess amounts. However, for healthy individuals the low
levels of phosphorus in the diet can be detrimental as it functions with Vitamin D and
calcium to maintain bone health.
4.
PTH
Calcitriol
Calcitonin
Serum calcium
increase
increase
decrease
Bone calcium
decrease
decrease
increase
Renal calcium reabsorption
increase
increase
decrease
Intestinal calcium
absorption
increase
increase
No effect
Serum phosphorus
both
increase
No effect
Bone phosphorus
decrease
decrease
increase
Renal phosphorus
excretion
increase
decrease
No effect
Intestinal phosphorus
absorption
No effect
increase
No effect
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