PSL201Y1 Final: pancreas

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8 Mar 2011
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\unqiue organ = has endocrine and exocrine portions. *when we discuss glucose metabolism and regulation, refer to pancreatic endocrine-made hormones. glucagon is catabolic, favours breakdown of energy storage to release nutrients (triglycerides fatty acids, glycogen glucose, protein aas) somatostatins are negative, they inhibit insulin and glucagon secretion. *metabolism = sum of all chemical reactions in the body. most of the pathways are tightly regulated in a stepwise fashion so there are multiple intervention points metabolic state i. *energy balance = control caloric intake and exercise. plasma glucose concentration is the most closely regulated of the three nutrient pools because glucose is the only fuel that the brain can metabolize, except in times of starvation carbohydrates glycogen liver, muscle glucose ((pathways)) metabolic state ii. catabolic (glucose, fat) storage fat triglyceride adipose tissue fatty acid + glycerol protein muscle amino acids www. notesolution. com. *glycogenolysis = breakdown of glycogen to glucose, stimulated under catabolic conditions.

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