Psy341 Jan 22 2013.docx

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Ross Hetherington

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Psy341 Jan 22 2013 Lecture 3 General etiological factors I: congenital anomalies Prevalence of congential anomalies Congenital anomaly: an abnormality of structure, function or metabolism that is present at birth, even if not diagnosed until later in life, that results in a physical or mental disability or is fatal. Not synonymous with genetic defect  Mortality rate has been reduced in the last 30 years  There are different factors that we understand  1. Genetic disorders o Single gene effects  Defects 1 in 250  Sickle cell diseases, cystic dibrosis, PKU, tay-Sachs  Polygenic (multifactorial) effects: autism, mental retardation, affective disorders, conduct disorders, ADHD, learning disabilities  Chromosomal anomaly: varies by region o Sickle cell  Health related quality of life (HRQoL)  Health: a state of complete physical, mental, and social well-being, nd not merely the absence of disease or infirmity  Why study HRQoL?  Describes health status  Identify different levels of morbidity  improve clinical decision m
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