TRN125Y1 Study Guide - Portal Hypertension, Hepatic Veins, Nephrotoxicity

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3 Feb 2013
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1. The lung that has fluid in the pleural space is termed and if it
occurs because disease of the lung has disrupted the Starling forces, it is
most likely .
a. Pleural Effusion, Exudative
b. Pneumothroax, Transudative
c. Pleural Effusion, Transudative
d. Pneumothroax, Exudative
2. Which cell covers most of the alveolar surface?
a. Type I Pneumocyte
b. Type II Pneumocyte
c. Avleolar Epithelial Cells
d. Macrophages
3. From the alveolus lumen to the blood vessel lumen the layers are as follows
in order:
a. Surfactant, basement membrane, interstitial tissue, alveolar
epithelium, capillary endothelium
b. Alveolar epithelium, surfactant, basement membrane, interstitial
tissue, capillary endothelium
c. Surfactant, alveolar epithelium, basement membrane, interstitial
tissue, capillary endothelium
d. Alveolar epithelium, basement membrane, surfactant, interstitial
tissue, capillary endothelium
4. The local or generalized fibrotic changes in the lung or pleura will cause
which type of Atelectasis?
a. Resorbtion
b. Compression
c. Contraction
5. Choose the incorrect statement about pulmonary disease:
a. Bronchitis, Asthma, Emphysema are all Obstructive Pulmonary
Diseases.
b. Obstructive Pulmonary disease is due to the reduced expansion of the
lung alveolar tissue (parenchyma).
c. Poliomyelitis, silicosis and kyphoscoliosis are all Restrictive Lung
diseases.
d. When having trouble breathing due to COPD it is not useful to try
breathing harder.
6. When a person presents with a fever of unknown origin, this is a medical
emergency and you most likely suspect:
a. Heart Failure
b. COPD
c. Inflammatory Bowel Disease
d. Vasculitis
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7. IgG and IgM can get lodged in the walls of the blood vessels and cause
vasculitis, what happens normally to stop this from happening?
a. These complexes are not formed
b. The endothelial cells have tight junctions
c. They are phagocytosed by macrophages in the spleen
d. Neutrophils are not activated
8. When should you not give steroids if you suspect vasculitis?
a. When the person has an infection
b. When the person has vasculitis caused by immune cross-reactivity
c. When the person has a fever of unknown origin
d. When the person has vasculitis is caused by p-ANCA
e. When the person has primary vasculitis
9. Which statement about ANCA is incorrect?
a. c-ANCA’s antigen is proteinase 3 in the neutrophil
b. c-ANCA is associated with Giant Cell Arteritis
c. p-ANCA is expressed in the rare form of vasculitis called Polyarteritis
nodosa
d. ANCA formation precedes neutrophil activation
10. T/F Heart failure occurs more in men than women.
11. T/F Right sided heart failure rarely occurs by itself.
12. T/F When you press on the abdomen, a positive reflex is when the
jugular venous pressure elevates and becomes more pronounced.
13. Which statement is false regarding heart failure?
a. The elderly typically have diastolic dysfunction
b. Mitral regurgitation occurs because of the sphericity of the heart
c. The cardiac myocytes undergo hypotrophy leading to heart failure
d. ADH is a powerful vasoconstrictor
14. How many patients die within 1 year of diagnosis?
a. 10-20%
b. 30-40%
c. 40-50%
d. 60-70%
15. Reduced ejection fraction is associated with:
a. Systolic heart failure
b. Diastolic heart failure
16. T/F A persons ability to participate in physical activity is commonly
used to determine the stage of heart failure.
17. What is not one of the common etiologies of systolic heart failure.
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a. Myocardial hypertrophy
b. Coronary artery disease
c. Myocardial ischemia
d. Dilated cardiomyopathy
18. When does dyspnea occur during lung function decline?
a. FEV < 4L
b. FEV <1L
c. FEV <2L
d. FEV <6L
19. T/F Forced Expiratory Volume normally declines with age.
20. What is mainly responsible for the destruction of the lungs?
a. Oxidative stress which destroys the protease inhibitors
b. The macrophages that secrete IL-8 and destroy the epithelial cells
c. Methacholine causing hyperresponsiveness of epithelial cells
d. The imbalance of protease to protease inhibitors in the lung
21. Which statement is false regarding emphysema?
a. Centracinar emphysema is typically associated with COPD
b. Paracinar emphysema damages the most distal part of the alveolus
c. The upper lung lobes are commonly affected by centracinar
emphysema.
d. It is common for the alveoli to be spared in asthma
22. What is not one of the most commonly involved sinuses in sinusitis?
a. Sphenoid
b. Maxillary
c. Anterior ethmoidal
d. Frontal
23. Identify the correct statement of the following regarding sinusitis:
a. Mucocele is when the sinus cavity is infected
b. Empyema is when the sinus cavity is non-infectious
c. The most common cause of acute sinusitis is a UTRI of bacterial origin
d. Optic neuritis is associated with the ethmoidal sinuses
e. Acute sinusitis is commonly followed by rhinitis
24. T/F The loss of alveolar attachments due to ECM destructions is a
feature in large airway changes.
25. The diagram below is an illustration of which inflammatory bowel
disease?
a. Ulcerative colitis
b. Crohn’s disease
c. Small bowel disease
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