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Midterm

BIOL 459 Midterm: BIOL 459 Vaccines

4 Pages
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Department
Biology
Course Code
BIOL 459
Professor
Roy Real

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Final Study Notes: Topic 7- Vaccines
Define:
Variolation
Vaccine
Inoculation of smallpox into Skin
Jenner inoculated cowpox to
prevent smallpox
vacca= cow
Suspension/fractions of organisms
that induce immunity
Effects of Vaccination
Provokes a primary immune response
Leads to formation of
antibodies/ memory cells
Produces rapid secondary response
What is herd immunity?
Immunity in most of the popn
Outbreaks are sporadic due to
lack of susceptible individuals
Immunizing the majority of
those that can will help protect
those that cannot get vaccines
Types of Vaccines
Live attenuated vaccines
Weakened pathogen; closely
mimics actual infection
Contributes to lifelong
cellular/humoral immunity
Inactivated killed vaccines
Safer than live!
Requires repeated boosters
Induce mostly humoral
immunity
Subunit vaccines
Antigenic fragments stimulate
immune response
Recombinant
Virus-like particles (do
not contain viral DNA)
Toxoids
Antitoxins
Conjugated vaccines
Used for children w/ poor
immune response
Nucleic Acid (DNA) vaccines
Injected naked DNA produces

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Description
Final Study Notes: Topic 7- Vaccines Define: Variolation Inoculation of smallpox into Skin Jenner inoculated cowpox to prevent smallpox vacca= cow Vaccine Suspension/fractions of organisms that induce immunity Effects of Vaccination Provokes a primary immune response Leads to formation of antibodies/ memory cells Produces rapid secondary response What is herd immunity? Immunity in most of the popn Outbreaks are sporadic due to lack of susceptible individuals Immunizing the majority of those that can will help protect those that cannot get vaccines Types of Vaccines Live attenuated vaccines Weakened pathogen; closely mimics actual infection Contributes to lifelong cellular/humoral immunity Inactivated killed vaccines Safer than live! Requires repeated boosters Induce mostly humoral immunity Subunit vaccines Antigenic fragments stimulate immune response Recombinant Virus-like particles (do not contain viral DNA) Toxoids Antitoxins Conjugated vaccines Used for children w/ poor immune response Nucleic Acid (DNA) vaccines Injected naked DNA produces
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