MICR 303 Study Guide - Midterm Guide: Cytosol, Lipoprotein, Benzene

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Document Summary

True nucleus: double membrane, nuclear pore complex. animal cells: (main focus) complex af-> organization increases complexity (dif. proteins required to move things out etc) having membranes around things. If have centrifuge tube w/increasing density, molecules move through until reach neutral density where they no longer sink or oat (stay there). spin for like 24 hours. Origin of organelles: nucleus and er -> invagination of membrane (double membrane, inside nucleus equivalent to cytosol) mitochondria/chloroplasts: arisen by endosymbiosis -> have own dna/cellular processes, topology. % of rer vs ser -> dictates how organelle works, The nucleus: nuclear pores: can move solutes in both directions. Dna replicate and transcribed in nucleus, but use proteins -> not int here. This forms heterochromatin -> highly condensed during replication. Gated transport, small molecules move freely through interior looks like mesh, larger molecules cant, must be actively transported. Pores anchored to the nuclear lamina (cytoskeletal structure holding nucleaus together)