MICR 303- Final Exam Guide - Comprehensive Notes for the exam ( 88 pages long!)

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Effector cells: molecules the body uses to protect against infectious agents, their toxins and damage they cause (unicellular) Important for in ammation (recruiting cells to infection site, activating more cells to help treat infection: adaptive immune system: Antigen speci c response -> immune cells respond to single antigen or pathogen by way of speci c receptors. Leukocytes: white blood cells lymphoid = adaptive, myeloid = innate. Hematopoietic stem cells in bone marrow -> give rise to all blood cells (white, red, platelets) -> pluripotent, most made here. Some form yolk sac in fetal liver -> travel from here and feed into different tissues (central nervous system), stay and mature into immune cells. Pathogens: disease causing microorganisms; vary in size/mechanisms of damage (dif size - > dif locations, in vs. out of cell) Commensal: microbe w/ symbiotic relationship to host (microbiome) no host damage. Viruses: obligate intracellular -> lyse out of cells.

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