BIOL 2070 Study Guide - Midterm Guide: Human Papillomavirus Infection, Orthomyxoviridae, Enterobacteria Phage T4
8 Feb 2017
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Bacteriocidal (plateau of total cell count, dip of viable cell count) Bacteriolytic (dip in both total and viable cell count) Protein damage is a common process for microbial controls. Plasma membrane: changes to permeability, destruction of the cell through lysis. Maybe even loss of water through osmosis. For mycobacteria and endospores you might want to use: Fo(cid:396) su(cid:396)fa(cid:272)es a(cid:374)d thi(cid:374) laye(cid:396)s of ai(cid:396) o(cid:396) li(cid:395)uid. Damages dna by forming an aberrant bond between thymines (thymine dimers) Ma(cid:374)y di(cid:373)e(cid:396)s a(cid:396)e lethal, (cid:272)a(cid:374)(cid:859)t repair fast enough. Direct damage: double stranded dna breaks (lethal) Indirect damage: water molecules are ionized to radical which can create damage! Must have water to allow for better penetration, protein denaturation. Soap and water is preferable to alcohol rubs. Sporicidal agents are recommended for use (sodium hypochlorite) Soluble and functions even when highly diluted. Readily delivered to the site of infection. Remains potent for long period of time and not metabolized prematurely.
