BIOC 3100 Study Guide - Final Guide: Electrochemical Gradient, Myocyte, Enoyl-Coa Hydratase

• School: University of Windsor
• Department: Chemistry and Biochemistry
• Course: BIOC 3100
• Professor: pandey

Document Summary

Please write name of the enzyme and the amino acids involved. the enzyme involved is branched alpha-ketoacid dehydrogenase. The amino acids involved are valine and isoleucine: regular and excessive intake of alcohol causes severe liver cirrhosis (liver damage). This produces a lot of nadh which inhibits enzymes of cac cycles, hence no atp production. What is the reason? less glucose in tissue ---glu(cid:272)o(cid:374)eoge(cid:374)esis(cid:894)o(cid:454)aloa(cid:272)etate i(cid:374) cac(cid:895) usi(cid:374)g keto(cid:374)e (cid:271)odies (cid:894) a(cid:272)etate to acetone) fatty oxidation and glycolysis ----produces lots of alpha-keto a(cid:272)ids gu(cid:272)(cid:374)o(cid:374)e i(cid:374) ph --- > pro(cid:271)le(cid:373) with (cid:271)ufferi(cid:374)g of h+ i(cid:374) (cid:271)lood tissue outpours water e(cid:454)(cid:272)retio(cid:374) of k+ , h+, e(cid:272)t (cid:373)aki(cid:374)g them thirsty: a starved subject is fed with radiolabeled alanine with (n^15 and c^14). The breath, blood, urine and liver samples are analyzed for chemical composition. Indicate the cofactors and products t each steps as well as the names of each enzyme involved.