Biochemistry 3386B Study Guide - Midterm Guide: Aids, Lipoprotein Lipase Deficiency, Coronary Artery Bypass Surgery

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As a part of a general physical check up of an apparently healthy person. As part of a diagnostic investigation of an unwell patient (abnormality in the lipid profile) Talks to the patient (history, documentation of symptoms etc. ) Physical examination (weight, height, blood pressure, hr) Women post-menopausal and/or 50 years old. Hypertension ( 140/90 mmhg or taking hypertensive medications may have forgotten to take their medications) note systeole/diastole. Current or recent (within the previous year) cigarette smoking. Family history of premature cad (coronary artery disease) <60 years in first degree relatives (ie. siblings or parents) Inflammatory disease: systemic lupus, erythematosis, rheumatoid arthritis, psoriasis) Evidence of atherosclerosis (hardening of arteries lesions) Hiv infection treated with highly active antiretroviral therapy. Manifestations of hyperlipidemia: xanthelasma, xanthoma, premature corneal arcus. Monogenic familial (genetic) lipid disorders (screen everyone in the family, including children) Minimum 9-12 hour fast (usually overnight; water is permitted) Stable weight over the past 4 weeks.

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