Biochemistry 2280A Study Guide - Final Guide: Acetyl-Coa, Mitochondrial Matrix, Intermembrane Space

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Identify the different metabolic fates of glucose-6-phosphate, and how these pathways are related. Turned into glucose: releases a phosphate group. Turned into ribose-5- phosphate: pentose phosphate pathway. Explain in general terms how glycogen is synthesized and degraded: first move the phosphate from the 6 position to the 1 position, glucose 1 phosphate glycogen. This is done by the enzyme glycogen synthase. Energetically favourable reaction, - g: glycogen glucose 1 phosphate. Activated by amp and inhibited by g6p and atp (there are other enzymes involved) Energetically favourable reaction, - g: not just the reverse process, the 2 different enzymes operate differently and allow this reaction to happen. Glycolysis: 1 molecule of glucose is oxidized to pyruvate, forming 2 atp and 2 nadh, other monosaccharides can also feed into glycolysis fructose, lactose. Will take any monosaccharide: oxidation of carbons occurs, need corresponding reduction, glycolysis makes energy and a reducing agent.

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