Biochemistry 2280A Study Guide - Final Guide: Enol, Hydrogen Bond, Uracil

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Explain the chemical structure of nucleic acid polymers, without memorizing the structures of the nitrogenous bases. Describe b-dna and the higher order structures formed by rna, and the important forces that stabilize these structures. Identify chemical and structural similarities and differences between dna and rna. Template for producing proteins (mrna) ( dna gets transcribed to this) 90% of your genome is transcribed into rna a lot of it are little rnas with regulatory functions. Composed of three parts a sugar, a nitrogenous base, and a phosphate. Forms a n-glycosidic bond because a nitrogen is involved vs. an oxygen. Sugar is always in b configuration in this bond (cannot switch back and forth anymore once in a bond) Use numbers to describe the nitrogenous bases (plain numbers) To number the sugar we put a prime to distinguish those atoms from the ones in the base. Base is always on the 1" carbon. Add a phosphate group on the highest number carbon.

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