Biology 2382B Study Guide - Midterm Guide: G1 Phase, Chromosome Segregation, Cell Cycle

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Learning objectives: cell cycle, mpf and control of g2 m transition, cell cycle regulation, dna damage checkpoint. Cells need to recognize checkpoints if possible mutations have taken place. Recommended readings (8th ed. : chapter 19: the eukaryotic cell cycle, pg 874-878; 881-886; 890; 895-897; 904-907. Essential mechanism by which all living things reproduce and pass on genetic information to next generation of cells. Ensures that dna in each chromosome is faithfully replicated to produce 2 copies: replicated chromosomes must be accurately replicated, divided, and distributed (segregated) to 2 genetically identical daughter cells. Not only do you have to divide the dna between the daughter cells, but also other elements: Transcription factors, ribosomes, golgi : coordination of growth (increase in cell mass) with division. Prior to mitosis, you need cell growth, so that you have enough materials to divide in 2. The cell cycle and its phases: cell cycle.

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