Biology 2382B Study Guide - Partition Coefficient, Glut1, Electric Potential

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The main determinants of diffusion are the partition coefficient and the concentration difference. No energy required; high concentration to low concentration. Partition coefficient (k): measure of the preference of a molecule to partition into a. Pores, channels, gates, uniports (glut1: pores and channels. Integral membrane proteins which create holes in the membrane, large enough for solutes to pass through. Used by cells to form charge gradient across membrane (electric potential: gates. Uses atp to move molecules against their concentration gradient. Classified by subunit composition, molecules transported, mechanism of action. Types of atp pumps: muscle ca2+ atpase (p class) Pumps 2ca2+ out of cytosol into sr per atp: na+/k+ atpase (p class) 3na+ out, 2k+ in per atp (antiporter: abc pumps aren"t setting up a gradient, just moving molecules from one side of the membrane to the other side. Na+ has high concentration out of cell and low inside cell; wants to move in to cell.

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