Biology 2382B Study Guide - Midterm Guide: Antonie Van Leeuwenhoek, Hat Medium, Green Fluorescent Protein
1 Mar 2016
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Document Summary
Historically, imaging using light microscopy has been a key tool for biologists from the outset - indeed, cell biology was literally born with microscopy. Seminal observations of robert hooke under the microscope (micrographia: led to the initial coining of the term cell (referring to a tiny bare room, similar to a monk"s cell). Since then, microscopy has revolutionized our understanding of how cells live and die. New subcellular compartments have been discovered thanks to improving microscopy techniques, and progress in cell biology sill relies in great part on advances in imaging technique. First to observe living protozoa and bacteria which he called animalcules Went on to visualize human red blood cells and sperm. With great skill at grinding lenses, naturally acute eyesight and lots of patience he was able to achieve a magnification of 200x. Compound microscope: microscope using more than one lens. Overall magnification = ocular lens x objective lens.
