Biology 2382B Study Guide - Final Guide: Microtubule Organizing Center, Tubulin, Centriole
28 Mar 2016
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Document Summary
Intricate network of protein filaments that extend throughout the cytoplasm. You can stain the different components with different colors. The names of the parts are respective of the size of the proteins. Transport moving towards and away are moving along the cytoskeleton. Note: in a cell there is no vaccym, thus no empty space. For example, although there appears to be empty space in blood its composed of lots of proteins, sugars, and lots of other things. Cell never separates the dimers, even during dephosphorylation. Basic building block that you have build microtubules with. Have polarity--> because they polymerize in the same orientation and order the filament will also have the same polarity. 25 nm diameter, up to 100s of um long. Can isolate with detergents to pull the dimers apart. A binds permanently to gtp, b can hydrolyze gtp so can be bound to gtp or gdp. As the polymer (protofilament) grows, b"s gtp is hydrolyzed.
