Biology 2581B Study Guide - Quiz Guide: Rubik'S Revenge, Inosine, Transfer Rna
Document Summary
61 triplet encode for 20 amino acids. Redundant: several codons for one amino acid) G or u, therefore there are multiple codons that code for the same amino acid (in bacteria only 31 trna molecules necessary to decode 61 codons) Aminoacyl trna synthetases = couple each amino acid to their appropriate set of trnas (anticodons) trna synthetases probe for chemical and structural complementarity with trna using one or more of several criteria: Structural features of trna all coupled amino acids go through editing site: correct amino acids do not fit, incorrect amino acids fit and are hydrolysed (accuracy with editing is about one mistake in 40,000 couplings) 2 adaptors in translation process: aminoacyl-trna synthetase, linking the correct amino acid to a trna, trna anticodon, binding to a matching codon on mrna. Proteins are synthesized from the n- to c-terminus, the protein chain is transferred to the incoming trna, amino acids are connected by a peptide bond.