Biology 3592A Final: [Biology 3592A] - Final Exam Guide - Everything you need to know! (52 pages long)
29 Nov 2016
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2: 95% of cases trisomy 21 is due to extra chromosome, but there is another 5% due to other reasons. Can talk about outcomes for number of pregnancy to see structural and numerical abnormalities. High mortality: spontaneous abortions, have very few live births compared to number of pregnancies, involves numerical abnormalities (involved autosomes), and unbalanced rearrangements (extra or missing genetic materials) trisomy or monosomy. Number of actual births relative to pregnancies, ex less then a quarter of trisomy 21 will survive. Translocations in general just exchange genetic information. Have chromosome that contains both q arms. When we lose the p arms of one or more acrocentric chromosomes normally not detrimental b/c so many copies of rrna genes on other acrocentric chromosomes. This individual will be 45 xx/xy so not really balanced but since both p arms of acrocentric chromosome, we consider it balanced.
