Study Guides (248,551)
Canada (121,622)
Biology (1,536)

October 20, 2011 - Luloff et. al

2 Pages
80 Views
Unlock Document

Department
Biology
Course
Biology 3594A
Professor
Kathleen Hill
Semester
Fall

Description
Radiation Exposure Differentially Affects Songbird 8hydroxy20deoxyguanosine Plasma ProfilesIonizing Radiation Damage Response in SongbirdsLuloff et alWhat does DNA damage by proxy meanCan use levels of different molecules in the body to measure DNA damage For example measuring 8OHdG levels in blood plasma particle that is released into blood plasma after irradiation can indicate levels of DNA damage What makes the two song bird species excellent subjects in the Luloff et al studyWith songbirds can study the effects of radiation easily because birds are easily captured and manipulated They can easily be compared to controls as well because songbirds from other areas that were not affected by radiation can be captured These species overlap in ranges geographically and show similar physiological and behavioural traits but differ in evolutionary life history Both songbirds have similar body mass wing length diet and have comparable metabolic rates Damage does not equal mutation explain DNA damage can be repaired by homologous recombination repair nucleotide or base excision repair and mismatch repair are wellknown mechanisms responsible for DNA damage regeneration DNA damage causes genotoxicity however it might not cause cytotoxicity or a ch
More Less

Related notes for Biology 3594A

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit