Biology 1001A Midterm: Biology 1001 Notes Part 2

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2. relative distribution of various components of genome sequence (junk vs. essential dna) Mobile elements: our examples have so far involved two participating dna molecules that have always been at least partially homologous and that have always originated from two different individuals. Insertion sequence elements and transposons are the two major types of prokaryotic mobile. This also means that tes do not exist free of the dna in which they are integrated; hence, the popular name jumping genes is actually inaccurate: tes a(cid:396)e (cid:374)e(cid:448)e(cid:396) (cid:862)i(cid:374) the ai(cid:396)(cid:863) (cid:271)et(cid:449)ee(cid:374) o(cid:374)e lo(cid:272)atio(cid:374) a(cid:374)d a(cid:374)othe(cid:396). The dna of many eukaryotes, including humans, contains a surprising amount of nonfunctional te sequence likely created in this way. 3. why african populations have more unique snps than other populations (ie. asian or caucasian). 5. why mobile elements are considered to be biological mutagens. 9. mechanism of chromosomal rearrangements resulting from double strand breaks. 10. role of uv, ionizing radiation and ros in mutagenesis.

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