Biology 1002B Study Guide - Midterm Guide: Membrane Fluidity, Secretion, Atp-Binding Cassette Transporter

• School: Western University
• Department: Biology
• Course: Biology 1002B
• Professor: Tom Haffie Denis Maxwell

Document Summary

O2: facilitated diffusion: molecules must have a transport protein to help molecules pass through the membrane, ex. The secretory pathway (components of itand what goes through it: this is how to get proteins to the plasma membrane, proteins that need to get out go through the secretory pathway. Protein targeting to the er and the role of the signal peptide: pathways to get to the plasma membrane, ribosomes are associated with the e. r. , and ribosomes can be detached from the e. r. Basics of simple and facilitated diffusion: simple: pass through freely without help, facilitated: pass through the membrane with the help of an active transporter. Transport against a concentration gradient (active transport: need an active transporter for molecules to go against the gradient. Linking transport with free energy changewhat drives transport: entropy drives transport. Basic structure of abc transporter: transmembrane domain and atp-binding domain.