Microbiology and Immunology 2500A/B Study Guide - Comprehensive Final Guide: Pattern Recognition Receptor, Intracellular Parasite, Innate Immune System
1 Dec 2016
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Document Summary
To protect us from microorganisms with the potential to cause infectious diseases, called pathogenic microorganisms or pathogens. 10 million in 1 ml of seawater. 40 million in 1 ml of saliva or 1 g of soil. Immune system has to decide if something is a threat since not all the pathogens are infectious. Use cells and proteins to sense treats. Sometimes the immune system gets it wrong. False response to non-harmful antigens (ex. pollen) Not a threat but body thinks it is ->generates allergies. Apoptosis: cell suicide, a natural process when the cell is damaged/worn out/old. Immune t cells attack and destroy the body"s own healthy cells. Microorganisms have the advantage of reproducing and evolving extremely quickly. Immune system has to try to keep up with the load. If the immune system is unable to destroy them all - you get sick. Infectious disease are transferable- can be passed on from person to person.
