Microbiology and Immunology 2500A/B- Final Exam Guide - Comprehensive Notes for the exam ( 164 pages long!)

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Introduction: to protect us from microorganisms with the potential to cause infectious diseases called pathogenic microorganisms or pathogens, e. g. bacteria, virus, parasite, fungi. Number of pathogens that cause serious human infections globally: 10 most burdensome infections diseases in ontario: hep c (** london), hiv/aids (**london), Hpv, hep b, influenza, rhinovirus, e. coli, staph, clostridium difficile, strep. Infections diseases remain the leading cause of death worldwide: major increase in life expectancy from early 1900s is mainly due to control of infectious diseases. Prevention and control of infectious diseases: the pathogen or the infectious agent uses a reservoir to reproduce and then has a portal of exit. Main immune components are: cells, some tissue cells, white blood cells called leukocytes, phagocytes and lymphocytes, proteins that are secreted by cells, cytokines, acute phase proteins e. g. complement proteins, antibodies. Blood cells are derived from a hematopoietic stem cell located in bone marrow 2 developmental paways for white blood cells.