Microbiology and Immunology 2500A/B Study Guide - Midterm Guide: Granzyme, Chemotaxis, Interleukin 10

• School: Western University
• Department: Microbiology and Immunology
• Course: Microbiology and Immunology 2500A/B
• Professor: Stephanie Kelly

Document Summary

Part i: the key properties of innate immunology, inherited from parents. Born with innate defenses (in utero: lasts 10 months; it"s transient) Can also be obtained by newborns via breast milk. Ii)always initiated when a pathogen contacts the body. Always working since we are constantly exposed to pathogens. Same immune response to identical pathogen with each. Non-adaptive: how barriers prevent pathogen entry into tissues. Receptors on innate immune cells recognize the pathogen pathogens. Receptors of the innate immune system are typically not clonally directly or signal for a cellular response. The binding of pathogens by these receptors gives rise to very imposed by the clonal expansion of cells needed in the adaptive immune response. Part ii: describe the steps involved in phagocytosis. Cell membrane extends around microbe and internalizes it into a phagosome. Phagosome fuses with lysosome containing antimicrobial components, forming a phagolysosome kills the pathogen. Releases its contents onto the infected pathogen to kill it.