Microbiology and Immunology 3300B Study Guide - Final Guide: Glycolipid, Twin, Antibiotics
29 Mar 2013
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Lecture 10 study notes: discuss organ transplantation. Before, assumed that organs could not be transplanted because individuals were too different suggested that immune response would kill the new organ. If you inject cells into a body, the immune cells will kill it off. If you inject it a second time, they will be killed even faster. But if you inject them into a newborn, then no immune response will occur because their system is not developed enough. Joseph murray transplanted between fraternal twins because he know immunological tolerance would occur. Found in humans to be on chromosome 6 and in miice chromosome 17. They formed the mhc complex major histocompatibilty complex. Class 2 dp dq dr dm, doa, dob class 3 are cytokines. Mice: class 1 h2 l h2 d, h2k, tab bp. Class 1 4 domains: alpha 1,2,3 and beta2microglobulin formed from gene 17 in humans and chromosome 2 in mice transmembrane protein.
