Microbiology and Immunology 2500A/B Study Guide - Rna Virus, Dna Replication, Cell Nucleus

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All living things have nucleic acids (dna)- only viruses can have dna or rna. Nucleic acids: a:t or g:c (a:u in rna) Dna replication= semiconservative (unwind and both strands copied) Direction of replication: template read 3"-5" & product made 5"-3". Ssdna must go through dsdna stage to make more ssdna. Rna viruses- most rna viruses are ss (some ds) Ssrna viruses: + sense (can be translated to make a protein, sense (cannot be translated to make a protein, ambisense (has both + and sense on the single strand) Rna virus must carry the rdrp with it because it cannot translate rna right away. +rna virus doent need to carry it because it can translate its. Rna into the rdrp in the cell, then use it. Dsdna= proviral dna can integrate into host chromosome e. g. retrovirus (with rt aka rddp) can make rna+ into. Unidirectional info flow (dna rna protein) Transcription: initiation, elongation, termination get primary mrna transcript.

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