Microbiology and Immunology 2500A/B Study Guide - Acinetobacter Baumannii, Hospital-Acquired Pneumonia, Klebsiella Pneumoniae

• School: Western University
• Department: Microbiology and Immunology
• Course: Microbiology and Immunology 2500A/B
• Professor: John Mc Cormick

Document Summary

Gram negative: yersinia pestis cause plague. Found in icus, burn unit: cause ventilator associated pneumonia, utis, bacteremia and sepsis, klebsiella pneumoniae causes nosocomial pneumonia. Meningitis under 5 after resp or ear infection. Gram positive: enterococci (vre) faecalis: more virulent less drug resistant. Faecium: less virulent more drug resistant: can be vancomycin resistant (vre). Cause utis, endocarditis: clostridia: rod shaped, endospore formers, anaerobes, in soil & animal gi tract. Toxin mediated diseases: difficile: pseudomembranous colitis (antibiotic-associated diarrhea). Can exist as asymptomatic carrier state, mild diarrhea or life-threatening pseudomembranous colitis. Treat with antibiotics can revert to highly resistant endospores. Die of asphyxiation/suffocation: botulinum: botulism food borne illness. Toxin causes paralysis: perfringens: food borne illness & gas gangrene (wounds heal while dirty heroine addicts, staphylococci biofilm associated infections. Extracellular pyogenic abscess: epidermidis: coagulase negative, produce capsule biofilm catheter, aureus: coagulase positive (clot blood). S. aureus enterotoxin food poisoning: antibody coated bacterium binds to fc receptor on phagocyte.