Microbiology and Immunology 3300B Study Guide - Final Guide: Macrophage, Cell Adhesion Molecule, Vascular Endothelial Growth Factor
29 Mar 2013
School
Department
Professor
Document Summary
Ibd = chronic inflammation of the gi tract can cause colon/rectal cancer (10% get it) Within the general population, 0. 05% develop colon or rectal cancer. Chemically altered forms of dna created by superoxide or hydrogen peroxide. Dna repair might fix them but sometimes it doesn"t: discuss inflammation, infection and cancer. Chronic infection can lead to cancer (helicobacter pylori = infection of the stomach) Oncovirus (enter infected cell and use gene to take over cell division) Infections may cause up to 25% of all cancers. Causes cervical cancer (5th most common in women) Hpv can also cause anal, vaginal, penile, head, neck and oral cancers: discuss the hpv vaccines. Drives angiogenesis to provide blood supply to the growing tumor. When it stops growing the tumour will secrete vegf which will cause new blood vessels to form, penetrate the tumour and allow more o2 and nutrients to expand.
