Pharmacology 2060A/B- Final Exam Guide - Comprehensive Notes for the exam ( 29 pages long!)
29 Mar 2018
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Document Summary
Pharmacology referred to as the study of drugs which includes many aspects, including: how a drug is delivered (route of administration, how a drug works (mechanism of action) Classification of therapeutics: drugs traditional drugs (aka. chemical agents/structures, biologics antibodies, hormones, natural health products herbals, vitamins, minerals. Drug development: preclinical testing (~6. 5 years, drug discover through cultured cells, living tissue, or experimental animals, evaluate biological effects, pharmacokinetics, and toxicity, clinical trial application (30 days, must be submitted to health canada prior to any human studies. Involves a lot of paperwork detailing all pre-clinical data: phase i clinical trial (~1 year, requires 20-100 health volunteers, evaluate pharmacokinetics and pharmacodynamics, phase ii clinical trial (~2 years) 300-500 patients with the target disorder: therapeutic effectiveness, side effects, and dosing info is gathered, phase iii clinical trial (~4 years) 500-5000 patients with the target disorder: therapeutic effectiveness verified, long term side effects assessed, new drug submission (~1. 5 years)
