[Pharmacology 3620] - Midterm Exam Guide - Comprehensive Notes for the exam (43 pages long!)

• School: Western University
• Department: Pharmacology
• Course: Pharmacology 3620
• Professor: Rommel Tirona

Document Summary

Section 1: introduction to pharmacokinetics membrane permeability of drugs. The goal of drug therapy is to prevent, cure, or control various diseases. Elements of a doctor"s prescription will contain in the following order & pharmacokinetics affects each part of the prescription: Dose (e. g. po = per os/by mouth) (volume of distribution is important) Dosing interval (depends on half-life, clearance, and volume of distribution) Small peptidic chains of up to tens of amino acids (usually hormones) Up to 30% of new drugs are proteins. Antisense therapeutics nucleotide chains which act together to inhibit the translation of gene targets. Peptides, proteins, and oligonucleotides must be injected rather than taken orally. Generic name: based on national and international (e. g. british and us) standards (e. g. Generic name: based on national and international (e. g. british and us) standards (e. g. paracetamol acetaminophen: the course will focus on these names. Brand name: what the company calls the drug (e. g. tylenol)