Physiology 4710A/B Final: Final Notes2.docx

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Transforming mechanical energy into electrical activity - pacinian: 1. Mechanical stimulus (eg. pressure) receptor"s onion like membrane: 2. Channels open and na+ flows through: inside of the receptor depolarizes more +) deforms the membrane (voltage becomes, 3. If the graded potential summed at the initial segment is above threshold, ap is generated and propagated down the axon: most touch afferents have myelinated axons in which ap hop from gap to gap, thus speeding up conduction. In any one part of your skin you will find 4 receptors: hair receptors (back of hand) or meissener (palm of hand, merkel. Labeled lines: for the brain to recognize that a stimulus is a vibration that is coming from the surface of the skin, the brain must label the afferent type that has been activated as an ra1 afferent. 2: each type of touch sensor has its own private line a labeled line.