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Digestion Lectures 1-6 These notes where made from a recording of the lectures, so the the notes are very accurate and detailed. Also, hints about possible test questions and other useful stuff that he says in lectures !

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Physiology 1021
Barry Tepperman

Digestion Lecture 1Appreciation of other units to understand GT Neurophysiology stomach has its own nervous system this affects activitystomach secrets peptides into bloodstream into body Cardiac output 13 of cardiac output goes to stomach Diagram of Digestive tractBasic function of the gut is to take in nutrients break them down and absorb themDoes them through the 3 major functions of the gut 1 Secretion2 major types exocrinerefers to hormones out of bodyendocrinesecreted into the blood stream2 Motility 3 Absorption Going to talk about endocrineexocrine Secretion Salivary Glands Primary digestion glandsbc they secrete an enzyme amylasebreaks down COH starts in the mouthonly COH starts in the mouthSubmandibularin the jawParotidin the mouthSublingualunder the tongue HC03bicarbonate neutralizes oral acidslike a citrus fruitalso neutralizes from oral bacteria bc lining of mouth is very susceptible to a low PHand tooth enamel is also very susceptible to low PHEnzyme work best at a neutral PHamylase likes a PH around 67 Salivary Secretion Converging Duct SystemPrimary ducts converging to a main duct into the mouth Starts off as a large functional unit and drains into a very small duct All these ducts converge eventually into one main ductTalking about formation of Saliva by looking at one of those converging ducts DiagramSalivon is the functional unit of secretion of the salivary glandsStriated duct and Acinus duct main ducts we are focusing onThere is a dense network of capillaries surrounding the AcinusSaliva is formed by plasma filtrationneed pressure for plasma filtrationmore pressure in the blood vessels concentration of salt in the Acinus lumen is isotonic to salt Striated ductactive transport system of Absorbs sodiumfor exchange of potassium Its a fixed rate active transport systemregardless of the level of stimulation Juice starts in the acinusmoves to the mouthit started as isotonic as it moves down to the mouth it becomes less concentrated And it becomes isotonic to plasmaHow do we get more juice formed in our salivary systemProcess is plasma filtration what do we do to get moreAnswer is we get more blood flowor change the perm and increase the pores and reduced barrier for the ions to flowAlso want to vasodilation the vessels As you pump more fluid through the Salivonthe efficiency decreases Summary At restthe juice in the Acinus is isosmotic to plasmaAt rest the juice in the mouth isisosmotic to plasma If it moves really fast it becomes less efficient and becomes hypotonic to plasma RegulationANS perm sympboth increase secretion1 Para nerves release AcH and it causes vasodilationcauses an increase in the aqueouswatercontent bc of the increase in plasma filtration and blood flow2Sympatheticcauses vasoconstriction opposite of permyou get secretion of glyco and mucuoproteinsthey are very stickymakes the mouth feel gummy and stickyDifference is a lot of water in PARA release and little in SYMP
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