Physiology 3120 Study Guide - Final Guide: Receptor Tyrosine Kinase, Thyrotropin Receptor, Thyroid Peroxidase

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Endocrine system: tissues and cells capable of secreting and responding to hormones, communication system these 2 components communicate via chemical messengers called hormones. Regulators of physiologic events (ie. low on glucose, hormone secreted to increase glucose: 2. Greek hormone, to rouse or set in motion. Different types of hormones: peptide/polypeptide, small monomers (eg. trh, 3aa, water soluble easily soluble in the blood. Large aromatic rings thus lipid soluble and require binding proteins. Human endocrine system (these are other, not as important: gut secretes its own series of hormones to regulate food intake and digestion (cck, ghrelin, gastrin, secretin, Between hormone and metabolite: pth from parathyroid gland acts on the bone (in this case) which produces ca2, ca2+ in the blood (the metabolite), high ca2+ stops the production of pth which contains ca2+ sensing receptors. Between antagonistic pairs of hormones: alpha cells make glucagon and beta cells make insulin (from the pancreas)