BIOL 1000 Study Guide - Midterm Guide: Peripheral Membrane Protein, Fluid Mosaic Model, Transmembrane Protein

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Fluidity of lipid bilayer is influenced by 2 factors: Keeping membranes in a fluid state is absolutely essential to cell function: temp too low: can inhibit functions, temp too high: membrane leakage. Two major types of proteins are associated with membranes: integral and peripheral membrane proteins. Membrane proteins can be separated into 4 major functional categories: Proteins that are embedded in the phospholipid bilayer are called integral membrane. Domain that interacts with lipid bilayer (hydrophobic core) is (cid:373)ostl(cid:455) (cid:374)o(cid:374) pola(cid:396) this fo(cid:396)(cid:373)s a se(cid:272)o(cid:374)da(cid:396)(cid:455) st(cid:396)u(cid:272)tu(cid:396)e (cid:272)alled a(cid:374) (cid:862)alpha heli(cid:454)(cid:863) The hydrophobic nature of membranes severely restricts the free movement of many molecules into and out of cells and from one compartment to another. Osmosis: diffusion of water molecules across a selectively permeable membrane: h(cid:455)poto(cid:374)i(cid:272): (cid:373)o(cid:396)e (cid:272)o(cid:374)(cid:272)e(cid:374)t(cid:396)atio(cid:374) i(cid:374) (cid:272)ell tha(cid:374) out (cid:449)ate(cid:396) (cid:272)o(cid:373)es i(cid:374) (cid:272)ell s(cid:449)ells, h(cid:455)pe(cid:396)to(cid:374)i(cid:272): (cid:373)o(cid:396)e (cid:272)o(cid:374)(cid:272)e(cid:374)t(cid:396)atio(cid:374) out of (cid:272)ell (cid:449)ate(cid:396) (cid:272)o(cid:373)es out (cid:272)ell sh(cid:396)inks.

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