KINE 3635 Study Guide - Midterm Guide: Attributable Risk, Osteoarthritis, Case Report

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 3635
• Professor: Hala Tamim

Document Summary

Testing a specific hypothesis about the relationship of a disease to a putative (presumed) cause, by conducting an epidemiologic study that relates the exposure of interest to the disease of interest. Start with people without the outcome, -> expose some of the sample-> follow up -> check for outcome. Direct measurement of incidence: the temporal sequence of exposure and disease can be directly addressed. Exposure clearly precedes the outcome because the population under study at baseline is free of the outcome of interest. Possible to examine a range of outcomes. Suitable for investigation of a rare exposure. Avoid recall bias (as the exposure is deter(cid:373)i(cid:374)ed (cid:271)efore the out(cid:272)o(cid:373)e, o(cid:374)e"s health out(cid:272)o(cid:373)e or disease state (cid:449)o(cid:374)"t affect how accurately one recalls exposure levels. ) Are the best observational study design used to help establish cause and effect relationship. If latent period is long, prolonged follow up is required (time- consuming). Not suitable for investigation of rare disease (rare outcome)