KINE 4505 Study Guide - Final Guide: Pars Compacta, Pars Reticulata, Basal Ganglia

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 4505
• Professor: Lauren E Sergio

Document Summary

180 during rest, bg continuously inhibits motor areas (tonic) inhibition must be removed before movements initiated. 2 main pathways: direct pathway: tonic inhibitory output & initiates desired movement projects to gp internal and sn pars reticulata indirect pathway: tonic inhibitory output & suppressed unwanted movement projects to gp external. 182 further inhibits thalamus and suppressed unwanted movements decreased speed of movements. Parkinson"s disease cell death in sn = loss of da. Bradykinesia: slow movements resting tremor in distal limbs. Da input from snpc decreases inhibitory output from bg. Ach producing cells in pedunculopontine nucleus =rigid hypokinesia. 187 pallidotomy: removal of gp internal = thalamus not inhibited = allows movements. Stn lesion: inhibition to gp internal = thalamic inhibition. Striatal neurons (gaba in caudate) in indirect path. Motor movement hemiballism: uncontrolled, involuntary flinging of limbs contralateral to lesion. Stn lesion - stroke decreased output from gp internal basic connectivity.