KINE 4010 Study Guide - Hematopoietic Stem Cell Transplantation, Sickle-Cell Disease, Hypertension

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108: looking at what happens at altitude, at seas level the pb is 760mmhg and gets thinner as you go up to altitude, fractions of the gases do not change (20. 93) 112: make yourself anemic by taking out rbc, and body creates rbc to compensate then you add the rbc back which increases your rbc content, withdraw blood, replace fluid loss with saline (diluting blood volume) Reduce hct <45 and hb to <15: kidney senses reduction of o2 delivery (ex. Take a razor blade to your wrist: risks: increases blood viscosity (better chance of blood clots, and cause strokes), increase resistance to blood flow and blood pressure, results: increase vo2max up to 25% and increase endurance. 113: how does epo work, when you have reduced o2 carrying capacity your under hypoxic condition, kidney (endocrine organ) detects this and secretes epo, epo acts on bone marrow to create rbc.

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