NATS 1670 Study Guide - Neuraminic Acid, Oseltamivir, Rna Virus
25 Mar 2015
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The influenza virus is an rna virus consisting of 8 rna segments (segmented genome virus) A glycoprotein found on the surface of the influenza virus: it is responsible for binding the virus to cells with sialic acid on the membranes: neuraminidase (na) enzymes. The second type of protein which assists the bonding of sugars that link neuraminic acids. By using oseltamivir (tamiflu), you can suppress na from doing its job. Oseltamivir (tamiflu: competitive inhibitor used to reduce the ability of the virus infecting us. How can we use the na and ha against the virus: antibodies against the influenza virus. Anti ha and na antibodies are great tools to fight infection and prevent disease. Antibodies that can bind to the surface of this virus are likely to stop ha from binding to the receptor on the surface of the cell and stop the activity of the na. Ha is blocked by the antibody helps other cells like macrophages destroy virus.
