BIOL2000 Study Guide - Midterm Guide: Carter Center, Trichinosis, T Helper Cell
Document Summary
Anterior end of both sexes shows 3 lips. Fertilized eggs are shorter and rounder than unfertilized eggs. Trichuris (whipworms) ingest eggs: embryonated eggs are ingested (infective stage, larvae hatches in small intestine and penetrate mucosa, adults in cecum, unembryonated eggs pass in feces (diagnosis, 2 cell stage, advanced cleavage. Moderate to heavy infection = abdominal pain, diarrhea, weight loss. Heavy infection in children = bloody diarrhea, cramps, rectal prolapse. Intestinal phase: worms attach to mucosa and feed on blood, leave bite site causing bleeding. Demonstration of characteristic eggs, champagne corks diagnosis eggs in feces mebendazole. Blackflies (larvae live in fast flowing oxygen rich water) Infection occur in proximity to fast moving water. Adult worms form nodules in cutis enclosed by host w/ fibrotic granuloma (onchocercoma) Microfilaria migrate through connective tissue and cause most of pathology once they die, enlisting inflammatory response (th2 response) Scratching = skin hardening and loss of pigment.
