NURS2204 Study Guide - Midterm Guide: Cardiac Arrhythmia, Unstable Angina, Orthostatic Hypotension
2 Oct 2016
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Digoxin- general mechanism of action, uses, side effects (must know these), monitoring/assessment before giving: cardiac glycoside, moa: increases the force of ventricular contraction and can thereby increase cardiac output. Positive inotropic actions: adverse effects: cardiac dysrhythmias. Nitrates- moa, uses (preventative also), side effects: moa: directly vasodilates vascular smooth muscle, and primarily decreasing oxygen demand for stable angina. Decreases oxygen demand: uses: acute angina therapy, sustained angina therapy. Iv for perioperative control of bp and treatment of heart failure with mi, unstable angina, uncontrolled exacerbations of chronic angina: adverse effects: headache, orthostatic hypotension, reflex tachycardia. Ranolazine (ranexa)- moa, uses, side effects: antianginal agents and anti-ischemic, moa: reduce sodium and calcium in myocardial cell and helps heart use energy better. Benefits modest and greater in men than in women. Can prolong qt, multiple drug interactions: uses: angina, adverse effects: constipation, dizziness, nausea, headache, drug interactions: most ccb"s inhibit cyp3a4 and increase levels of ranolazine, can give with amlodipine.
