NUSCTX 11 Study Guide - Midterm Guide: Cytochrome P450, Ed50, Inflammation
8 Jan 2019
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Department of nutritional sciences and toxicology (100 pts. Answer each question by selecting only one of the possible responses. Please indicate quiz group a on the answer sheet. Questions 1-7: jessica is a graduate student who isolated 2 chemical compounds, j1 and j2, from an unknown mushroom species she found in tilden park. J1 is fat soluble whereas j2 is water soluble. She fed mice with diet mixed with j1, and she found that j1 can reduce inflammation, but higher doses induces immune cell death. These mice initially look sluggish, lose the ability to move, and eventually die. Below is the dose response curve for j1. Name _______________________: a lower ed50, a lower loeal, jessica also found that j2 is very toxic. Using rodents as a model, she found that the ld50 of j2 is. This is because: they have one normal and one mutant copy of alcohol dehydrogenase.
