[BIOL 311] - Midterm Exam Guide - Comprehensive Notes for the exam (43 pages long!)

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History: william withering, physician 1700s helps arrhythmias foxglove (purified by william withering): has extract that can treat heart patients, comes from digatella flower slows rate, inc rate of contraction. Parsley and dill - extracts are new source of precursor of gva - an anti mitotic drug now more easily synthesized. Pomegranates have a component that when transformed by microbes in the gut prevent muscle cells from aging and recycle components to make new mitochondria aging cells struggle w mitophagy - getting rid of old dysfunctional mitochondria. Transplants w/o a waiting list demand is higher than supply. 3d tissue engineering may alter the transplant landscape. Problems - need scaffold stem cells may be used in future to generate new organs. Nanomedicine a very broad definition - primarily means using something small (nano particles) or small techniques for gene editing selective target (may be a sickle cell, tumor)

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