BIOL 311- Final Exam Guide - Comprehensive Notes for the exam ( 75 pages long!)
29 Mar 2018
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Study guide: experiment with parabiotic mice share a common circulatory system (make them that way) Aged serium does not work as well. The younger, the better: growth substrate, cell culture plates, microcarriers = beads, roller bottles (like the 7-11 hotdog rollers) Used for capillary endothelial cells: microporous membrane. Can be used to make engineered human epidermis. Use a cell culture to generate artificial tissues and/or organs: biological scaffolds, 3d meshwork that can be biodegradable to which cells attach, allows cells to build/grow 3 dimensionally. Cells will normally grow only linearly: made my robert lamger and joe vacanti at mit, cells used, human cells, autotransplant, possible to use animals. Double knockout is in 1,3 galactosyl gene no immune rejection: engineered tissues/organs that are out there today, human bladders. Used for children with spina bifida (4-19 year old) Neo-bladder works: elad extracordoreal liver assist device. Human, liver cell line cancer: divide in culture, 50% of cyt p450.
