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COMPLETE Cell Biology (CM) Notes -- 4.0ed this course!

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Department
Biology
Course
CAS BI 203
Professor
All Professors
Semester
Winter

Description
!"#$%&'($)&*+,"+-& & .$/0&12&34+&560789+%+07#&$#:&5+%%&;7,+)+#0& • 560789+%+07#2&:6#$)"/70+"#&="%$)+#08&+(0+#:"#?&04/[email protected][email protected]& 04+&<607>%$8)&7=&+& o .78"0"7#"#?&7=&7/?$#+%%+8& o 5+%%&)7,+)+#0& o 1#0+/#$%&7/0& • C<0"#2&)$"#&<60789+%+0$%&>/70+"#!&>7%6)+/"D+8&07&=7/)&$<0"#&="%$)+#08A&& o C<0"#&)7#7)+/!&E%[email protected]%$/&GEH&$<0"#& o C<0"#&="%$)+#0!&!"%$)+#[email protected]&G!H&$<0"#& o I")+/8&7=&E&$<0"#J&4+$:J07J0$"%&"#0+/$<0"7#& o E&$<0"#!&:")+/8!&0/")+/8!&!&$<0"#& o !&$<0"#J&F$/F+:&GKH&+#:&07&>7"#0+:&GJH&+#:8& o EJ$<0"#&F"#:8&C3.&$#:&46:/7%6D+8&"0&07&CI.&7#7%6)+/"D$0"7#&M&/$0+&7=&:"8877"#0+:&+#:A& o 3/+$:)"%%"#?J&7#+&+#:&7=&="%$)+#0&?/7-8N&-4"%+&04+&704+/&+#:&"8& 84/"#9"#?A& " C3.J)7#7)+/8&$::&07&F$/F+:&+#:A& " CI.J)7#7)+/8&:"8877"#0+:&+#:A&& o 1)>7/0$#0&>/70+"#82& " !7/)"#!&"#"0"$0+8&$<0"#&>7%6)+/"D$0"7#A& " C/>&OPQ!&"#"0"$0+8&="%$)+#0&F/$#<4"#?A& " 346)78"#!&>/+,+#08&+%7#?$0"7#&F6&F"#:"#?&[email protected]@#"08A& " ./7="%"#!&8>++:8&+%7#?$0"7#&F6&F"#:"#?&[email protected]@#"08A& " CI!P<7="%"#!&8>++:8&:"887+8&7=&$<0"#?&80/@<[email protected]/+82& " [email protected]#:%+8J&788J%"#9+:&"#07&$<9+:&>$/$%%+%&$//$68!& :7#+&F6&8)$%%&/"?":&>/70+"#8A& • .$/$%%+%&[email protected]#:%+J&[email protected]>>7/08&)"7,"%%"!&)$:+&F6&=")F/"#A& • 57#0/$<0"%+&[email protected]#:%+!&)$:+&F6&SJ$<0"#"#A& " T+0-7/98J&788J%"#9+:&"#07&7/047?7#$%&$//$68&=7/)"#?&QI& )+84-7/98A& • I7#+&F6&%$/?+&=%+("F%+&>/70+"#8A&& • U+%:&07?+04+/&F6&="%$)"#J&$&788&%"#9"#?&>/70+"#A& o !%+("F"%"06&:+0+/)"#+:&F6&F+0$&84++0A& o C<0"#&$#:&5+%%&$:4+8"7#& " C:4+/+#8&[email protected]#<0"7#8J&"+#:+#0HA& ! !"##$%&'()*+&,-".)/0+ • 1(&0.$%"%2(&0"+)0'"3()0+4/)0",+'/+&5')0+26+17+8')0+ &0,+9)05:#)0;(:3.+&??"5')03+&5')[email protected]+ ! !6'/5-&.)0$+A("9"0'.+"#/03&')/0+26+2)0,)03+'/+2&(2",+"0,.B"+A/P"(+.'(/I"+ ! E''&5-+E1B"+("#"&."+&5')0+ + ment (NF) proteins (designated NF-L, NF-M, and NF-H for light, medium, and heavy, respectively). These proteins form the major intermediate fila- ments of many types of mature neurons. They are particularly abundant in the axons of motor neurons and are thought to play a critical role in sup- porting these long, thin processes, which can extend more than a mett:!rin length. Another type IV protein (a-internexin) is expressed at an earlier stag• of!"##$%&'"(")*$pment prior to expression of the neurofilamen t pro- teins. The type V intermediate filament proteins are the nuclear lamins, which are found in most eukaryotic cells. Rather than being part of the,$("(71,)"8$ cytoskeleton, the nu!lea9)'21&)(")*,#$62-),#"$5:,)-"$6:,0"$eus where they assemb le to form an!ort!"##$;2##$(&'"$*&$*:"$#&5,*2&)$&4$*:"$62-),#8$$ brane and extending more diffusely into the nucleus (see Figure 9.5). Nestins (the type VI intermediate filament s) are expresst:!dduring embry- ! ?",>2)-$">-""$)";$,5*2)$42#,(")*6$4&1(2)-$,)>$)";$ onic deve lopment in sev,>:"62&)68$$of stem cells. They differ from other intermediate filaments in that they only polymerize if other intermediate filaments are present in the ceJl;nestins are sometimes classified as another type IV rather a type VIintermediate filament.2)$("6:;&1B$,)>$42#&0&>2,"$,5*2)$ Despite considerab le diversity in size and amino acid sequence, the var- iou
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