CAS BI 213 Study Guide - Final Guide: Operon, Ubtf, Transfer Rna
Document Summary
Rna polymerase and tranx: central dogma = dna transcription > rna translation > protein, all cells inherit same genes, so regulation of expression is what makes one cell different from another, e. coli rna polymerase: synthesizes rna in 5" to 3" direction, like dna pol. has 6 subunits (figure 7. 1, bottom unit s = promoter recognizer; detachable from 5 core polymerase units; specialized to different conditions (e. g. starvation vs. nutrient availability, core pol. unit is rna elongator, rna pol. does not need a primer like dna pol. Can synthesize rna de novo at the beginning of a gene\ s subunit required for correct identification of transcription initiation sites \ can bind to dna template and just begin replication (figure 7. 3: promoter: pol. binds to this sequence to start tranx of genes downstream, in prokaryotes, two sets of sequences at 10 and 35 (position relative to tranx initiation site at +1) are similar in many genes (figure 7. 2)
