CAS PS 231 Study Guide - Midterm Guide: Nmda Receptor, Encephalization Quotient, Neuroplasticity

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Synaptic plasticity for physiological psychology: brain is born and developing plasticity, mature brain subtle plasticity. Infancy, childhood, dendritic growth & pruning & myelination. Ltp, ltd - changed in synaptic strength. Even once brains are mature, synapses are formed and wiring diagram is stable, the connections can become more or less active spatial memory. Protein trafficking (where the protein is in the cell) including increased postsynaptic ampa glutamate receptors. Mg+ (large) block exits nmda glu receptors. As your synapses want to become more active and you have more activation of retrograde messengers, the higher voltage of the cell causes the mg+ block to come off voltage. Gated receptor (only when nmda reaches positive voltage and nmda receptor can be activated when glutamate binds) Strength of different synapses changes with age. Calcium ion of plasticity in the mature brain. How much calcium determines the strength of a synapse. Environmental experiences can change brain wiring even after maturation.