BCHM-3050 Study Guide - Comprehensive Final Exam Guide - Protein, Covalent Bond, Carboxylic Acid
20 Nov 2018
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Arrhenius acids: compounds that form h3o+ if dissolved in water. Why do they accept electrons? ph scale: based on auto-ionization of water. Amphoteric: water is able to react as acid or base. Biologically relevant weak acids and their conjugate bases. Note: conjugate acid/base pairs differ by one proton. Most bio rxns take place b/w ph 6. 5 and 8. 0. Buffer: resist changes in ph following addition of acid or base that have + 1 ph units difference from pka of solution. +3 ph units: the group is deprotonated or fully protonated and the buffer effect ceases ph = pka of solution: group is 50% protonated/deprotonated. Henderson-hassel bach equation: can be used to calculate average charge on ionizable group at any ph. A- : base ph < pka: concentration of acid is greater than concentration of base ph> pka: concentration of acid is less than concentration of base. Acetic acid buffer (hoac pka = 4. 76) containing 1m hoac and 1m na+ oac-
